When guano bats, Tadarida brasiliensis, inhale ammonia in air mixtures, carbon dioxide is passively retained in sufficient amounts to neutralize alkali excess resulting from increased blood ammonia levels. There is no change in blood carbon dioxide levels in house mice, Mus musculus. Little brown bats, Myotis lucifugus, are intermediate in this respect. Passive carbon dioxide retention is clearly related to ammonia tolerance in these mammals.
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