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Methods for the synthesis of fluoro containing benzazoles and benzazines from fluoroarenes (fluoroanilines, fluorobenzoic acids, fluoroacetophenones, fluorophenols, etc.) are described. The potentialities of the most important synthons are considered. Ways of constructing hetero cycles with fluorine atoms in the annulated benzene fragment are discussed.

Fused pyrimidine derivatives R 0515 Synthesis of 5-and 7-Fluoroquinazolin-4(1H)-ones. -Simple and convenient routes to the title quinazoline derivatives are presented. -(LAYEVA, A. A.; NOSOVA, E. V.; LIPUNOVA, G. N.; TRASHAKHOVA, T. V.; CHARUSHIN*, V. N.; Russ.

A New Approach to Fluorinated 4(3H)-Quinazolinones. -Fluorinated quinazolinones are synthesized based on the reaction of o-halogen substituted benzoyl chlorides with S-ethyl isothiourea and subsequent intramolecular cyclization of the S-ethyl N-benzoylisothioureas obtained. Nucleophilic substitution reactions at positions C-2 and C-7, as well as alkylation at C-1 of quinazolinones are described. (Some yields not given). -(LAYEVA, A. A.; NOSOVA, E. V.; LIPUNOVA, G. N.; TRASHAKHOVA, T. V.; CHARUSHIN*, V. N.; J. Fluorine Chem. 128 (2007) 7, 748-754; Postovsky Inst. Org. Synth., Russ. Acad. Sci., Ekaterinburg 620219, Russia; Eng.) -H. Toeppel 44-152