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autograft (AT), group 2. After 90 days, the quality of the formed bone block, the X-ray density of the bone tissue (RBCT) of the HU unit, its microhardness (MT) according to Vickers (HV), the mineral saturation (MH) of the bone tissue according to the parameters of calcium (Ca) and phosphorus (P) were studied on the spine preparations, the nature of osteogenesis. Results. In group 1, RPKT was 1.5 times higher than the general parameters of RPKT in group 2 (P <0.00833, taking into account the Banferoni correction (PB). In the first group, type 1 bone block according to Tan (2007) was formed, in the second this was not observed. MT it was the same as the bone of the bed, but exceeded these indicators in the second group, respectively, by 1.37 times (P <0.008333; taking into account the PB). The general indicators of MT also significantly differed in favor of group 1. Conclusion. When performing interbody fusion under conditions of fixation of the spinal segment with ceramic implants, the allogeneic bone graft has a greater regenerative potential, which contributes to the earlier formation of organ-specific bone tissue (degree of mineralization and strength) than a bone autograft.