Objective: To detect the microwave-assisted synthesis of Tetrahydropyrimidine derivative and its molecular docking studies for Diabetes. Methods: The Bignelli condensation method was used for Tetrahydropyrimidine derivative synthesis. The docking studies made in Argus Lab software. Results: The Tetrahydropyrimidine is synthesized using the microwave. The Tetrahydropyrimidine derivative is found to be attack the insulin receptor, as it the tendency of binding with insulin receptor showed in Argus lab. Further, the good binding site of Tetrahydropyrimidine derivative with insulin receptor was predicted. Conclusion: From the research work, The Tetrahydropyrimidine derivative shows its affinity to bind with the insulin receptor. The binding value is averagely 7 which indicates it can attraction with the receptor, so it can control Diabetic mellitus by altering insulin secretion in blood plasma.

Moringa olifera is a traditional medicinal plant that belongs to family moringaceae. It is also called as "Miracle tree". It is rich in alkaloids, flavonoids, essential amino acids and considered as one of the highly nutritious plants. Moringa olifera a multiuse plant is used as a food and medicinal uses. It has various pharmacological activities such as analgesic, antiinflammatory, antipyretic, anticancer, antioxidant, nootropic, hepatoprotective, gastroprotective, antiulcer, anticancer, antioxidant, hepatoprotective, gastroprotective, cardiovascular, antiobesity, antiasthamatic and antidiarrheal properties. This review is a collective summary of phytochemical, pharmacological activity and therapeutic importance of this medicinal herb. Moringa olifera has numerous medicinal uses and it is used to treat many diseases conditions. The review has focused on various properties of Moringa Olifera and therapeutic importance of moringa olifera and its chemical constituents Moringa oleifera is considered to be one of the beneficial plant which has higher medicinal values. Its various nutritional properties made the people across the world to use for its health benefits. The leaf of moringa is considered to have more effective property in curing many diseases though other parts of Moringa oleifera possess less effective properties. The chemical compound of Moringa leaf has high content when compared to other parts and some chemical compounds are present only in leaf of Moringa. Moringa leaf can be used for various health conditions such as Anaemia, Diabetes, Asthma, Inflammation, and Ulcer, Tumor growth, Microbial growth and Plasmodia (Malaria). Anaemia is one of the threatening disorder which is spread all over the world, anaemia occur due to various conditions in which majority is iron deficiency anaemia due to low iron content in plasma. The decrease in haemoglobin will give rise to anaemic condition. From traditional medicine literature study, IDA can be treated by daily consumption of Moringa leaf syrup. The review work focus on the medicinal uses, chemical composition and effect of Moringa leaf on Iron deficiency anaemia. The Moringa plant has interesting fact that it is used in war as energy drink, historical evidence shows Maurian troops uses Moringa juice as energy drink. It is also named as "Miracle Tree" due to its high medicinal values.