We report 2 observations of primary anorectal melanoma, collected over a period of 2 years from December 2017 to December 2019, as well as data from the literature. The patients nevertheless benefited after the histological evidence with an additional immunohistochemical study of an extension assessment made by pelvic MRI and thoracoabdominopelvic CT scan. The patients were classified stage I according to the Slingluff classification. They underwent abdominoperineal resection with definitive left iliac colostomy and adjuvant Chemotherapy.

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This article focuses on the symptomatic and diagnostic problems of primary duodenal adenocarcinoma by way of two case reports and a literature review.The diagnosis of primary duodenal adenocarcinoma is often delayed because its symptoms may be absent until the tumor has progressed, thus leading to a delay of several months. Patients typically present with a long history of variable and vague symptoms, and many are diagnosed with advanced disease. As regards clinical manifestations, abdominal pain is the most frequent symptom. The majority of these tumors are found to have infiltrated the duodenal wall at presentation, with many being unresectable due to local and distal invasion.

Highlights Retro rectal tumors are a rare group of tumors, its diagnosis is still very difficult. Are asymptomatic in most cases. Most retrorectal tumors ultimately require surgical resection.