We report three cases of eosinophilic meningitis in young male Rottweiler type dogs in New Zealand. No cause for the disease was identified. There were variable clinical signs referable to central nervous system dysfunction, and a variable response to treatment.
A female bearded dragon (Amphibolurus barbatus) died following intermittent periods of inappetance. No significant gross lesions were found at autopsy, but histological examination revealed disordered liver architecture with numerous foci of coagulative necrosis. Eosinophilic intranuclear inclusions were present in many hepatocytes, some epithelial cells of the bile ductules and occasional epithelial cells of renal tubes and glomeruli. Large numbers of viral particles within many nuclei, associated with the intranuclear inclusion were demonstrated by electronmicroscopy. Similar particles, sometimes in paracrystalline arrays, were also seen within membrane-bound vesicles located next to the nuclei and to a lesser degree within the cytoplasm and extracellular spaces. The virus was considered to be an adenovirus on the basis of its size, morphology, site of formation and lack of envelopment. It was considered to he the cause of the hepatitis.
The clinical, gross, histological and immunohistochemical findings were consistent with a diagnosis of lipoleiomyoma expressing oestrogen receptors. CLINICAL RELAVANCE: A lipoleiomyoma should be considered a differential diagnosis for a benign tumour in the caudal reproductive tract of the bitch. Incisional and fine-needle aspiration biopsies of a lipoleiomyoma may resemble a lipoma. Excisional biopsy may be required for a definitive diagnosis. Lipoleiomyomas in the reproductive tract of the bitch may possess sex steroid receptors, and patients may benefit from ovariohysterectomy or hormonal therapies prior to excision.
Résumé
Les papillomes viraux développés sur le doigt d’un chien ont été retirés et ont récidivés à quatre reprises en deux ans. Malgré la « persistance » des papillomes, ils sont restés petits et confinés aux doigts, et n’ont pas disséminés ou ne se sont pas aggravés. Tous les papillomes persistants ne progressent pas, même si ils sont traités avec des traitements plus conservateurs.
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