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This paper presents results of our analysis on gender and age differences in the effect of childhood stressful events on severity of anxiety and depression symptoms, coping behaviors and inherent personality traits in patients with affective disorders. The study included 440 patients hospitalized in our neuropsychiatric clinic. The results showed that in women childhood stressful events are associated with severity of anxiety and depression symptoms, as well as with some coping strategies and inherent personality traits, with some variability in different age groups. In men, a significant association with childhood stressful events was observed only with severity of depression and with scores for neuroticism. The associations in men also varied between different age groups.

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