Laccase is an important industrial enzyme used in the paper, food and textile industry. It is produced by many different organisms, including filamentous fungi. Trichoderma asperellum LBKURCC1 is a strain isolated from Riau soil, which can produce laccase by solid state fermentation (SSF) of rice husk and rice straw. The aim of this work was to optimize SSF production of laccase from rice straw, through optimizing Nitrogen, Carbon and surfactant supplements to the fermentation media. Effect of surfactant, nitrogen supplement, and carbon supplement were evaluated by using a Central Composite Design (CCD) and surface response analysis. The concentration of the surfactant, Tween-20, at all concentration levels tested had no significant effect to the model. In contrast, the nitrogen and carbon supplement concentrations were significant factors (P-Value<0.05) enhancing laccase production. Optimum conditions for laccase production were 23 g/L nitrogen and 1% carbon supplement, giving a maximum laccase activity of 56.8 U/L enzyme extracted, equivalent to 0.7 U per g rice straw fermented. Optimizing the nitrogen and carbon supplement increased yields up to 3 times the level obtained in a non-optimized media.

Explaining the development and relationship between science philosophy and Islamic philosophy is the aim of this writing. Descriptive qualitative is the method used by collecting data through library research to gain the aim. The result shows that the development of science philosophy can not be separated from the history of developed science which is the main base in the development of science in which science philosophy consists of (ontology, epistemology, and axiology) Islamic philosophy is based on Islamic notions led by revelation from Allah which are the absolute truth. Science philosophy is only the trigger since all theories and concepts have already been given in Al-Qur’an. Thus, science philosophy and Islamic philosophy can work together to create science based on absolute truth.