ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

2,1-b][1,3,4]thiadiazole-5-carbohydrazide. -A novel set of compounds such as (IV) is synthesized and tested in the NCI cytotoxicity panel. Among all derivatives compound, (IVb) is the most active one. -(TERZIOGLU*, N.; GUERSOY, A.; Eur. J. Med. Chem. 38 (2003) 7-8, 781-786; Dep. Pharm. Chem., Fac. Pharm., Univ. Istanbul, Beyazit, TR-34452 Istanbul, Turk.; Eng.) -K. Schneider 01-111

The mercaptoimidazole (I) is coupled with the chloroacetic acids (II) to produce the sulfides (III).

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Some 3-Hydrazono-2-indolinones and N-Mannich Bases as Potential Anticonvulsants.-A series of 3-hydrazono-2-indolinones, e.g. (III), and N-Mannich bases such as (VI) are synthesized and investigated for their anticonvulsant activity. It is shown that the introduction of bromo and morpholinomethyl substituents does not affect the desired activity. -(GUERSOY, A.; KARALI, N.; BUEYUEKTIMKIN, S.; DEMIRAYAK, S.; EKINCI, A. C.; OEZER, H.; Farmaco 51 (1996) 6, 437-442; Dep. Pharm. Chem., Fac. Pharm., Univ. Istanbul, TR-34452 Istanbul, Turk.; EN)