Digoxin is used to treat heart failure and arrhythmias. Even though its used is decreased, the toxicity of digoxin still remains a problem for physicians. We present a case of a middle-aged male pharmacist, diabetic, who intentionally ingested a toxic dose of digoxin and insulin with his random blood glucose (RBS) of 40mg/dl. He was hemodynamically stable and his ECG showed no arrhythmias. His initial investigations showed normal potassium level and digoxin level of >7.51ng/ml. He was closely observed in the emergency Department (ED). Patient was admitted to the hospital for close observation. Even though the patient's digoxin level was toxic; his potassium levels were within the normal limits, and his vitals and serial ECGs were all unremarkable. These Findings shine the light regarding the insulin and digoxin, in that the insulin maybe a life saving intervention in case of digoxin toxicity.
Although carbamate pe5ticides are widely uscd. research nCL'i shown that they have various side effects. The aim of thLs study was therefore to i11vestigate rhe cytogenetic effects of Lannate on mice. Another aim of the study was to investigate the protective effect of otiue oil against the cytogenetic eJjects of Lannate. 36 Swiss albino mice were exposed to uarlnus concentmtions of wnnate. Larma{e and olive oil. or were kept as controls. J\ntmals were sampled at two dOCferent tunes (24 UJ1d 48 hrs). Lannate iIl-creCL<;ed the rumtber of structural and numerical Chromosomal aberrations per celt On contrary. Lannate produced no effects 011 the rote of ceU diuLsion (mitotil: index) at et• cher 24 or 48 hrs. Moreouer. the use of olive oit gave promising results against Lannate toxicity as i1 significantly decreased the frequency of chromosomal aberratiOns.
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