The article presents a range analysis of the registered immunobiological preparations on Ukrainian market with a emphasis on inactivated vaccines against Newcastle Disease in poultry, as well as the results of comparative immunogenic efficacy evaluation of inactivated vaccines of domestic manufacturer Biotestlab Ltd and products of importer manufacturer. According to the List of Veterinary Immunobiological Preparations, 594 veterinary immunobiological preparations are registered in Ukraine as at October 5, 2020 where 84 of them are live and inactivated vaccines against Newcastle Disease in poultry. These vaccines are mono- and polyvalent and represent 14.1 % of the total number of immunobiological preparations. Inactivated vaccines against Newcastle disease are represented by 35 preparations, which is 5.9 % of total quantity and where 23 % are monovalent and 77 % are polyvalent - in which a component against Newcastle disease are one of the valent. According to the results of comparative studies of mono- and polyvalent vaccines against Newcastle disease of domestic manufacturer «Biotestlab» Ltd and vaccines of the importers was found that all studied drugs are immunogenic and provide protection of poultry sector against Newcastle disease.