Purpose The purpose of this paper is to verify the possibility of ultrasonic intensification of drug dissolution of cholesterol calculi of the gallbladder using conventional ultrasound frequency and intensity from 0.1 to 0.5 W/cm2. Design/methodology/approach For research purposes, the physical model was developed containing pig bile, pig liver, pigskin, fat and muscles, as well as human cholesterol calculus removed by surgery and a drug with ursodeoxycholic acid. Findings The studies have shown the possibility of accelerating the drug dissolution of calculi of the gallbladder with ultrasound exposure. The ultrasound intensity of 0.4 W/cm2 is the most preferable to intensify the dissolution of calculus. Originality/value The results will be used to advance with development of the device and methodology for ultrasonic intensification of drug dissolution of gallbladder calculi.

Treatment of patients with peripheral artery diseases is one of the most difficult issues in vascular surgery. The overall prevalence of peripheral arterial disease varies from 3-10% among the population aged 40-59 years old and among people over 70 years old - up to 15-20%. In the majority of cases atherosclerosis is the main cause of peripheral arterial disease. Autovein is considered a prosthesis of choice and is the most commonly used graft in the bypass surgery. However, it has been deemed impossible in 30% of cases due to its diameter, length or varicose lesions. Despite the technical advances, has not yet developed an ideal vascular prosthesis. Thus, there is a need of search for new materials and modifications of available materials, with the goal of creating a prosthesis for properties close to ideal. In this article we present first case report in the world about usage xenograft with protective external tubular mesh made from superelastic shape-memory nitinol as bypass material. This case shows that the xenoprosthesis with external tubular nitinol mesh support for prophylaxis of aneurysm formation can be used as vascular conduits in bypass surgery. Further randomized controlled trials needed.

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Biological liquids (blood particularly) imbibe 3-D construction of nikelid-titan porous plates easily. Clot formation takes place in large porous volume, its retraction by fibrin fibers forming and then maturation of connective tissue all together additionally fix the implant in bleeding zone.

ФГБУ «Новокузнецкий научно-практический центр медико-социальной экспертизы и реабилитации инвалидов» Минтруда России, г. Новокузнецк ГБОУ ДПО «Новокузнецкий государственный институт усовершенствования врачей» Минздрава России, г. НовокузнецкПроведен анализ лечения 196 пациентов с наличием культи бедра, страдающих атеросклерозом, осложнениями сахарного диабета и облитерирующим тромбангиитом. У 45 больных имелись признаки ишемии культи (наличие болей в покое, язв, некрозов), и реампутация выполнялись значительно реже, чем у больных без признаков ишемии. У пациентов, которым выполняли реконструкцию внутренней подвздошной артерии, показатели выживаемости существенно не отличались от таковых в контрольной группе. Установлено, что в развитии ишемии культи бедра важное значение имеет нарушение проходимости подвздошного сегмента. Обоснован способ пластики внутренней подвздошной артерии с использованием аутоартериального трансплантата.Ключевые слова: ишемия культи бедра, методы лечения, выживаемость, пластика внутренней подвздошной артерии.Analysis of treatment of 196 patients with hip stump, atherosclerosis, complications of diabetes and obliterative thrombangiitis was performed. Among these patients there were signs of ischemia of the stump in 45 patients (rest pain, ulcers, necrosis), and no signs of ischemia of the hip stump in 151 patients who had undergone conservative treatment or the hip reamputation was statistically significantly lower, than in patients without signs of ischemia. There was no significant difference between survival indexes of the patients who had undergone a reconstruction of internal iliac artery and those in control set. It was found that obstruction of the iliac segment is crucial in the development of the ischemia of the hip stump. A method of laceration of the internal iliac artery with the usage of autoarterial transplant was developed.Key words: hip stump ischemia, treatment methods, survival, laceration of the internal iliac artery.