No abstract

досліджувався вплив алелів генів короткостебловості (Rht) на проростання ліній-аналогів пшениці м'якої озимої в умовах осмотичного стресу. Встановлено, що наявність у генотипі алелів Rht веде до більшої редукції довжини колеоптиля у стресових умовах в порівнянні з умовами нормального водозабезпечення. Ключові слова: осмотичний стрес; пшениця м'яка озима; гени короткостебловості; Rht; довжина колеоптиля.

A pharmacoeconomic study of the rationality of the use of various chemotherapy regimens (“7 + 3” scheme) in the treatment of patients with acute forms of myeloid leukemia has been carried out. The use of the chemotherapy regimen “7 + 3” with 200 mg / m2 / per day dosage of cytarabine on 1-7 days allows to achieve a unit of treatment efficacy at a lower cost (CEA = 19.22 US $ / per unit of efficacy), compared with another dosage of cytarabine that was two times less, i.e., 100 mg / m² / day at the same period (CEA = US $ 20.18 / unit of effectiveness). The presented research results can be used in the formation of programs for the rational use of limited resources in the purchase of anticancer drugs for hematological cancer patients, as well as in the development of schemes for providing them with effective medical care in a hospital setting.

ф

One of the pathognomonic signs of сardiac allograft vasculopathy is concentric intimal hyperplasia, which can be assessed by intravascular imaging techniques. Early detection of cardiac graft vasculopathy and timely correction of immunosuppressive therapy can help slow the pathological process and, as a result, increase the functional survival of the heart graft. Recently, the method of intravascular optical coherence tomography, which improves the accuracy of the assessment of the layers of the vascular wall and is considered as an alternative to intravascular ultrasound, is becoming more and more common. This review focuses on the importance of modern methods of intravascular imaging in the early diagnosis of cardiac graft vasculopathy and the identification of predictors of this disease.