Recently study of the “silicon wire - nerve tissue’ interface has been in the focus of attention due to its potential use in recovering nervous system damage caused by injuries or diseases. The key objective of this research was to test the physicochemical state of the interface and to study its properties. Although much research has been done in this field, the process of interface formation was not thoroughly described from the surface physics point of view. In the current research specimens of the “silicon wire - nerve fiber" interface were made. Experiments were carried out in vivo. The interface morphology and mechanisms of adhesion were examined in more detail and a physical model of intermolecular interaction of silicon surface and nerve fiber was proposed.
Immunohistochemical analysis of changes in neuroma after surgical treatment of damaged peripheral nerve with the use of high frequency electrosurgical device for high frequency current welding of soft tissues was carried out. No adverse effects of this technology and the bipolar instrument on degeneration and regeneration of damaged nerve stem were detected.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.