Metal matrix syntactic foams (MMSF) are foam composites obtained by filling hollow and/or porous particles into a metal matrix. MMSF are promising materials in defense, aerospace, automotive, marine and engineering applications. Mechanical and physical properties of MMSF can be tailored to reach better structural and/or functional behaviors by fitting processing and tailoring parameters. Some of these parameters are: reinforcement size, volume fraction, distribution of reinforcements and chemical composition. Three techniques are available to manufacture MMSF: Stir casting/vortex method (SC), powder metallurgy (P/M) and infiltration routes. Infiltration process is by far the main employed for making MMSF, it allows a large range of reinforcement (30 vol % to 78 vol %) and offers great advantages compared to other techniques. This paper reviews infiltration routes used to date, their advantages and drawbacks, the main processing parameters of each route, and a relation of representative studies developed to date on the synthesizing of MMSF by molten infiltration processes.