Purpose: To observe the blood picture of patients with COVID 19 infections and to formulate future guidelines for management. Methods: This cross-sectional descriptive study was carried out among patients with COVID 19 infections who were admitted to one of the Covid-dedicated hospitals in Bangladesh from March-2020 to May-2020. Results: A total of 92 patients were included in this study. 53.3% were male and 46.7% were female. Most of the patient’s haemoglobin percentage was found below normal (53.3%), however, the total count of RBC, WBC and Platelet was found within the normal limits in most of the cases (64.1%,80.4% and 87% cases respectively). 75% of patients had high ESR levels. 50% of cases showed Neutrophilia and Lymphocytopenia in 43.5% cases. Although some cases show changes in Monocyte, Eosinophil and Basophil count they were not significant in number. Conclusions: A significant number of patient’s neutrophilia and lymphocytopenia. Blood parameter is an important tool for managing the COVID-19 patients. With or without co-morbidities maintaining normal blood levels is essential in COVID-19 patient management.