The three indices performed equally well during the induction phase and were able to predict the level of consciousness of the patients satisfactorily. During maintenance, the IoC and the BIS showed good agreement with the clinical signs. The CSI was significantly influenced by the administration of atracurium; therefore, the agreement with the OAAS scale during the maintenance phase was significantly less for CSI than for IoC and BIS.

The response of a susceptible coffee cultivar (Caturra) to infection by the root-knot nematode Meloidogyne exigua was compared histologically with that of cv. Iapar 59 possessing the recently identified Mex-1 resistance gene. The reproductive behaviour of the nematode was also compared in the two cultivars. Penetration and development in resistant plants were reduced in comparison with susceptible plants. Several cell features, including dark-stained cytoplasm and altered organelle structure, were observed in the resistant cultivar, indicating a hypersensitive-like (HR) response of the infested host cells. Features of giant cells were sometimes found beside necrotic-like areas, but the corresponding feeding sites were frequently associated with nematodes displaying abnormal shape. Six weeks after inoculation, root systems of cv. Caturra contained significantly more nematodes than those of cv. Iapar 59 (mean values 1574 and 41, respectively). The susceptible cultivar presented a minimum of 11 galls per plant, compared with only one or two galls per plant in the resistant cultivar. The findings are discussed in the context of plant-pathogen interactions.

Despite the complexity of the interview, the majority of families consented to ICOD. Estimating the probability of BD and assessing medical suitability are additional challenges of the practice. ICOD represents a clear opportunity to increase the donor pool and ensures organ donation is posed at every end-of-life care pathway.

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