The efficiency of autotransplantation of the thyroid tissue into the greater omentum was demonstrated in experiments on rats. High viability of the transplant and restoration of the hormonal thyroid activity were attained after a single injection of the cell suspension of autologous adherent bone marrow cells directly into the transplant.
Surgical thyropathy correction is inevitably accompanied by specific change s in hormonal status. We have analyzed the ada ptation mechan - isms and compensat ory and adaptive reactions responsible for the whole life-support system of organism. On the basis of a number of organism homeostats nonspecific mechanism s of resistant and tolerant realisation strategies of long-term adaptation were studied, suppositions were made on possible effective course of adaptation reactions in the conditions of healthy thyroidal issue transplantation and cellular therapy use.
The efficiency of thyroid tissue autotransplantation was studied in 150 male Wistar rats for 3 months. Comparative analysis of functional competence of the thyroid tissue transplanted into the great omentum showed restoration of the thyroid hormonal activity in animals receiving cell suspension of autologous adherent bone marrow cells.
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