No abstract

Important in the pathogenesis of many diseases of the cardiovascular system plays a decrease in elasticity and stiffening of the large arteries. Currently, one of the leading places is devoted to the study of the role of the vascular wall in the pathogenesis of hypertension. A number of studies indicate that an increase in the rigidity of the arterial bed is an independent factor of cardiovascular risk: at the same time, the risk of coronary artery disease, stroke, dissecting aortic aneurysms, and overall mortality from cardiovascular diseases is higher.

Vascular stiffness is an independent prognostic parameter for the development of cardiac pathology and cardiovascular mortality. The predictive value is high at the preclinical stages of the development of the disease, since blood vessels are an integral marker of cardiovascular pathology, through which classic risk factors for cardiovascular diseases (CVD) are realized. Vascular stiffness increases due to cholesterol deposits and calcification of the vessel wall. On the other hand, an increase in blood pressure (BP) causes changes in the vascular wall, including with the development of arteriolosclerosis, which can also lead to an increase in vascular stiffness.

Coronavirus infection is a group of infectious diseases caused by various serotypes of coronavirus (SARS-CoV, SARS-CoV-2), and in severe cases is dangerous for the body and human health. During the pandemic of the new coronavirus infection COVID-19, neurological disorders were noticed in patients, which were manifested by the following symptoms and pathological conditions: dizziness, headache, ischemic stroke, intracerebral hemorrhage. As statistics show, these manifestations were noted mainly in patients with vascular pathology, coagulopathy, and in cases of severe multimorbidity. Stroke is the main cause of persistent neurological disorders and death, therefore, it requires a more detailed analysis of the course of the pathology, patient management and preventive measures.

Лекции для врачей Диагностика и лечение болезни Крона В статье представлены сведения об этиологии и патогенезе болезни Крона, современная клaссификaция, клиническая симптоматика заболевания, а также диaгнoстикa и oснoвные подходы к терапии и профилактике.