Highlights An experimental study of R1234yf as a drop-in replacement for R134a is presented An alternative methodology was proposed to estimate the optimal mass charge R1234yf optimal charge was 92.2 g, about 7.8% lower than R134a A thermal and energy comparison between R134a and R1234yf was analyzed The TEWI analysis for the R1234yf was 1.13% higher than for R134a
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