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According to epidemiological studies, bacterial rhinosinusitis is one of the most common pathologies of ENT-organs on an upward trend. Rhinosinusitis significantly reduces the patient’s quality of life and, in the absence of timely treatment, can lead to serious complications. Macrolide antibiotics are effective drugs in the treatment of rhinosinusitis. Roxithromycin (Esparoxy), one of modern macrolides, showed good results. The article provides characteristics of this drug, reflects the high quality of efficacy and safety in the treatment of bacterial rhinosinusitis, with due regard to the experience of the Russian and foreign authors.

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