Tuberculosis (TB) is an insidious and airborne infectious disease caused by Mycobacterium tuberculosis that mainly affects the lungs. TB is one of the top 10 leading causes of mortality worldwide from a single infectious disease (above HIV/AIDS). In 2018, the World Health Organization (WHO) estimated about 10 million people fell ill with TB worldwide while 1.5 million died as a result of TB infection (0.25 million among people living with HIV) (World Health
The antimicrobial activities of chloroform, methanol and aqueous extracts of the bark of Gymnanthes lucida, Gliricidia sepium, Lysiloma divaricata, Lysiloma tergemina and Coccolaba cozumelensis were tested against S. lutea, E. coli, S. epidermidis, L. monocytogenes, S. choleraesuis, S. aureus, P. aeruginosa, B. pumillus, S. typhimurium, P. vulgaris, V. cholerae and C. albicans. It was found that methanol extracts of the two Lysiloma species and G. sepium had antimicrobial effects against S. epidermidis, S. aureus, P. aeruginosa, B. pumillus and V. cholerae at doses of 200 microg. The major inhibitory effect was observed with L. tergemina which showed a bacteriostatic effect on S. epidermidis at doses of 400 microg/mL.
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