No abstract

Corpora cavernosa of 4 impotent patients with arterial pathology and 6 with venous insufficiency were studied by electron microscopy. The findings in all of the smooth muscle samples were the following: pronounced thickening of the basal lamina; marked reduction of contractile myofilaments and electron dense bodies; finger-like cytoplasmic projections; increase in mitochondria with swelling and aggregation; huge protrusions of nuclear membrane into the cytoplasm; increased proportion of interstitial matrix to smooth muscle cells. These were more marked in the dark than in the light cells, which was considered as the beginning of degeneration. Another finding was degenerative changes in the endothelial cell lining of the sinusoids, especially denudation, fragmentation and marked thickening of the basal lamina. Severity of the symptoms did not change in any of the patients with different pathologies. So, we can assume that the pathological alterations may be due to chronic penile vascular insufficiency or vice versa.

No abstract

Ancak, haşlangıçta )lüksek değer giiıteren talil/klarda bir azalma (P < 0.05), düşük değer gösterenleıde ise bir artış (P.

Sunınıary:The respoııse of eclis, appeared in gastro-intestinal mucosa and called by different names (such as enterochromaffin, argentaffin, argyroplıil, basal granulated, bright or yellow cells) according to the staining characteristics, against to the different biologicly active matcrials, have been reported by many authors. This study has been earried out to clarify the effeet of exeess salt (natrium ehloride) administered perously, on these eells.In this study, 20 matUl'e albino rats, divided into 4 groups, were used. Eaeh animal was fed with 10 g of dry matter per ı00 g of body weight, daily, and was allawed to drink water ad libitum. The control group reeeived the normal daily salt requirement (0,5 percent of daily dry matter), while the other tlıree groups reeeived 5 times of this daily requirement for periods of 7 days, 14 days and 30 days, respeetivel}'.The samples were obtained li'om the upper part of duadenum. For eounting of enteroehromaffin ce lls by lightmieroseope, Gomori's methenamine silver method were used.The ultrastruetural charaeteristies were studied, under Carl Zeiss EM 9 5-2, in the seetions, fixed according to Kamovsky method, seetioned by LKE ultratome III and staincd by Icad eitrate.There has been found an inerease in the number of enteroehromaffin eells, that showed a statistieally proportinal parallelism to the duration of salt intake. The findings obtained by light-and eleetronmieroseopes were as follows: Thcse eclIs whieh were prismatieal in villi and pyramidal in erypts, were in a direct relation to the [umen. The surfaee eontai-