Optimizing the treatment of purulent-inflammatory diseases of the maxillofacial area is one of the urgent tasks of maxillofacial surgery, this is due to a number of objective reasons, which include changes both on the part of the macroorganism and on the part of inflammatory agents. The purpose of the study was to search and analyze scientific sources in Ukraine and the world, regarding the latest methods of treatment of odontogenic phlegmon, features of their course and complications. To study the research materials, we used the bibliosemantic and analytical method, with the help of which we processed literary data, as well as research materials that were posted on the Internet. Phlegmons of the maxillofacial area and neck are divided into: 1 group (mild course) phlegmons that are localized in one anatomical area; 2nd group (medium severity) phlegmons are localized in two or more anatomical areas; 3rd group (severe course) phlegmons are localized in the soft tissues of the floor of the oral cavity, neck, half of the face, as well as a combination of phlegmons of the temporal area, subtemporal and pterygoid fossa. From the obtained results of the clinical examination, phlegmons were found in (80%) patients with lesions of one facial space, in (15%) patients with involvement of two spaces, (4%) with three spaces, and (1%) with lesions of four or more. On the basis of the used bibliosemantic and analytical methods, with the help of which we processed literary data, we believe that the study of the problems of methods of treatment of odontogenic phlegmons remains a relevant topic, to which numerous works of both domestic and foreign scientists are devoted. But at the same time, there is no consensus on the conservative therapy of these diseases, especially in the presence of concomitant pathology, which has a significant impact on the features of reparative processes. Therefore, solving this problem requires further comprehensive study.