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Aim and Objective: Microleakage is the most important factor responsible for the destruction of restoration margins. The aim of this study was to compare and evaluate the microleakage of three different restorative materials namely glass hybrid restorative system, zirconomer improved and Cention N under stereomicroscope. Materials and Methods: In this in-vitro experimental study, 45 Class V cavities were prepared on the buccal surface of maxillary premolars. The prepared cavities were divided into three groups for restoration with Cention N(group I), Zirconomer Improved(group II), Equiaforte (group III). All the samples were thermocycled for 500 cycles between 5-55°C initially and then immersed in 0.5% methylene blue for 24 hours before sectioning. All the sectioned samples were observed for microleakage under a stereomicroscope. Results: Data was analyzed using one way ANOVA test for comparison between three groups and the result revealed statistically significant difference between the groups(p<0.05). Post hoc Tukey test was used for intergroup comparison and it was observed that both Cention and Equiaforte are inferior to Zirconomer improved in terms of microleakage (p<0.05). Conclusion: Zirconomer improved exhibited lower microleakage when compared to Cention N and Equiaforte cements.

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