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Behavior of membranes derived from collagen was investigated in rabbit corneas. Disks of the membrane were placed between the lamellae of corneas which were then examined grossly, biomicroscopically, and histologically. The membranes remained clear, and almost no reaction or evidence of reabsorption was seen during an observation period of 6 months. These characteristics make the material potentially useful for heterotransplantation in the cornea.