The aim of this study was to search for small bowel lesions by means of a perioperative endoscopy in 20 patients operated on for Crohn's disease. Seven women and 13 men (mean age 29 years) had a total retrograde exploration to the angle of Treitz during an ileocolectomy (16 of20 patients) or a colonic or ileal resection (four of20 patients). Endoscopic exploration was completed, through an enterotomy, from the surgical area to the angle of Treitz. Periendoscopic biopsy samples were taken on macroscopic lesions and every 20 cm systematically. In 13 of 20 cases, various lesions scattered over the whole small intestine were found. These were aphthoid ulcerations (10 patients), superficial ulcerations (seven patients), mucosal oedema (three patients), non-ulcerative stenosis (three patients), erythema (two patients), pseudopolyps (two patients), deep ulcerations (two patients), and ulcerative stenosis (one patient). In seven patients none of the lesions detected at perioperative endoscopy had been recognised by preoperative evaluation or surgical inspection ofthe serosal surface. A typical granuloma was found at biopsy of lesions identified by endoscopy in three cases and at biopsy of an apparently healthy area in one case. Thus 65% ofpatients operated on for Crohn's disease had lesions of the small intestine detected by endoscopy, which were unrecognised before surgery in more than half of the cases.
Wu r tz: Ueber einen Aldehyd-Alkohol. 457 di 0 bet reffend e Oriyi nalabha nd I u ng (Corn p t. rend. 7 I, 462) zu Gesicht zu bekommen. Ails einer kurzen Bemerkung in der letztern schliesse ioh nun, dass die genannten Cherniker die oben beschriebene Aethylurarnidobeneoesaure ebenfalls bereits beobrchtet haben niiissen, indem sie sagen, dass sich auch ,,die t'reie ArnidobenzoEsaure, Amidocuminsiiure u n d Amidoanissaure mit cyansaurem Aethyl verbinden konnen und dnss die dabei entstehenden Korper denjenigen aus den betreffenden Aethern sehr iihnlich seien."
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.