No abstract

In many livestock farms in Russia there is a problem of correct balancing rations by the major mineral elements. Mineral metabolism disturbance are accompanied by various pathologies from all body systems, including the reproduction function. Timely conducting clinical examination, including hematological examination of all groups of animals allows to prevent the development of negative conditions in the body of cows associated with impaired mineral metabolism. During 2018, 74 blood samples obtained from newly‐calved cows were investigated. All the animals had various signs of mineral failure ‐ lordosis of the lumbar spine, osteomalacia of the caudal vertebrae and the last pair of ribs, weakness of the ligaments of the finger joints. With biochemical research of serum determined that the concentration of total protein averaged 90.7 ± 5.9 g/l, albumin −27.3 ± 3.7 g/l, globulin −61.4 ± 3.2 g/l, which indicates hypoproteinemia with dysproteinemia, with the concentration urea increased to 9.5 ± 0.4 mmol/l. The alkaline phosphatase level in fresh cows was 122.1 ± 11.1 IU/l, AST activity was 130.8 ± 5.6 IU/l, and ALT −34.7 ± 3.9 IU/l. The concentration of cholesterol and triglycerides in the blood of the studied animals were quite high and amounted to 8.7 ± 0.3 mmol/l and 0.29 ± 0.06 mmol/l, accordingly, indicating a violation of lipid metabolism. Ca : P ratio in the cows' blood was disturbed and was often 2: 1.9. The amount of total calcium in the blood was at the level of 2.25 ± 0.03 mmol/l, and of phosphorus −2.09 ± 0.03 mmol/l. During the morphological research, it was determined that the number of red blood cells in cows was lower than the reference values and amounted to 4.3 ± 0.4 * 10^6 /μL, the hemoglobin concentration was 84.0 ± 4.8 g /l, anemia was observed in erythropenia and hypochromemia. Also, in cows with signs of impaired mineral metabolism in the postpartum period, a decrease in hematocrit to 29.0 ± 0.5% was observed. The number of white blood cells was within the reference values and was 9.7 ± 0.5 *10^9/l. In the analysis of leukograms, neutrophilia was identified with the appearance of young cell forms, which suggests a possible course of the inflammatory process. Thus, it can be concluded that carrying out timely medical examination of fresh animals in violation of mineral metabolism will allow to assess the prospects for further use of cows and, taking the necessary measures, to extend their productive longevity.This abstract is from the Experimental Biology 2019 Meeting. There is no full text article associated with this abstract published in The FASEB Journal.

In order to prevent mammary gland' disease, the specialists of InterChemmet LLC, to-gether with scientists from the St. Petersburg State Academy of Veterinary Medicine, have developed a hygiene product. "Compomol DS +" is used to treat the skin of the nipples of the udder before milking. It thoroughly and quickly cleanses the skin from various contaminants and helps to activate milk flow. Since the gate for the penetration of staphy-lococci and streptococci into the udder is an open nipple canal, foam treatment of each nipple was carried out. The nipple was dipped into a foaming glass with a 40% solu-tion of Compomol DS +. After that, the nip-ple was wiped with a soft napkin. Another product called Compomol DS Green Eco developed by InterChemmet LLC is applied to the udder nipples immediately after milking. The drug helps to normalize blood circulation after milking, has a wound healing property. The drug forms a mem-brane. This limits the access of microflora to the udder through the nipple, since the sphincter of the nipple canal remains open for 30 minutes after milking. When using «Compomol DS Green Eco» for 180 days, no negative effects on the skin of the nipples were observed. After hygienic treatment of the nipples, the animals be-haved calmly while putting on cups on the nipples and during milking, which contribut-ed to the complete extraction of milk from the mammary gland. The amount of residual milk after milking was not more than 40-60 ml of milk. An analysis of the results of the research indicates that the above hygiene products reduce the incidence of cows with mastitis by 33.4% and do not cause harmful effects to both animals and the staff. Using of hygiene products on the farm in 96 cows with-in 180 days of the experiment allowed to reduce economic damage by 39900 rubles. Measures aimed at prevention of cow’s mastitis incidence.

No abstract