It is shown that a potential difference, the value of which depends on the spin state of electrons, appears in the vicinity of the system of electrons floating on the surface of liquid helium in an inhomogeneous magnetic field.
ГБОУ ВПО «К расноярский государственный медицинский университет им. проф. В. Ф. Войно-Я сенецкого», г. К расноярск 2М едико-санитарная часть № 24 Ф едеральной службы исполнения наказаний Р осси и , г. К расноярск Цель: проанализировать возможности проведения хирургического лечения больных туберкулезом легких, сочетанным с ВИЧ-инфекцией, в условиях пенитенциарной системы. Материалы и методы. Проанализировано 7 случаев хирургического лечения больных туберкулезом легких в сочетании с ВИ Ч-инф екцией в туберкулезной больнице Ф С И Н России с 2013 по 2015 г. Результаты. Хирургическое лечение (резекция легкого) было успешно выполнено у 7 больных туберкулезом в сочетании с ВИЧ-инфекцией. У 5 из 7 больных были туберкулемы легких, у 1-ф иброзно-кавернозный туберкулез, у 1-инфильтративный туберкулез, осложнивш ийся спонтанным пневмотораксом. Распространенность туберкулеза была от 1 до 4 сегментов, стадия ВИ Ч-инф екции-Iffi, III, Ш Б , среднее число CD4 в крови-693,0 ± 98,3 клетки/м кл. Кроме химиотерапии, в пред-и послеоперационном периоде использовались: лимфотропное введение, фитопроцедуры и пневмоперитонеум. Ключевые слова: туберкулез легких, ВИ Ч-инф екция, хирургическое лечение, пенитенциарная система.
Funding Acknowledgements
Type of funding sources: None.
Background
Patients with single ventricle defects may develop Fontan-associated liver disease. T1 mapping has been successfully used for evaluating chronic liver disease in adults. Liver T1 mapping has been also studied in the pediatric patients with single ventricles, and these patients show higher T1 relaxation times compared to the healthy controls.
Purpose
Our objective was to study the relationship between the cardiac MRI (CMR) T1 mapping relaxation time of the liver and 1) CMR derived hemodynamic parameters, 2) peripheral venous pressure (PVP) measured from a cubital cannula 3) systemic ventricle morphology [LV vs. RV], 4) the age of patient, and 5) alanine transaminase (P-ALAT) levels.
Methods
This retrospective study included 46 patients with functional single ventricle, which underwent routine CMR at our hospital. Table 1 shows demographic and clinical data of the study population. Statistical analysis were performed with IBM SPSS Statistics v.25 software using independent samples t test, Mann-Whitney U-test or Pearson correlation as appropriate. A p-value less than 0.05 was considered significant.
Results
The average T1 relaxation time of the liver was longer in patients with RV morphology (p = 0.004). There was a significant moderate positive correlation between the age of the patients and hepatic T1 relaxation time (r = 0.45, p = 0.002), and between hepatic T1 relaxation time and P-ALAT levels (r = 0.5, p = 0.016) (Fig.1). No significant correlations were detected between the T1 times of the liver and hemodynamic parameters of the heart (all tested parameters are listed in the Table1). Ejection fraction and PVP showed a non-significant weak correlation with a hepatic T1 relaxation times (r=-0.3, p = 0,056 and r = 0.3, p = 0,070, respectively).
Conclusions
T1 mapping times of the liver may reflect Fontan-associated liver disease. We observed connections between the hepatic T1 relaxation times and 1) patients age, 2) systemic ventricle morphology and 3) P-ALAT levels.
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