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The purpose of the study — to identify and evaluate the clinical significance of “hidden” disorders of blood oxygenation in smokers with exacerbation of bronchial asthma.Materials and methods: spirometry, pulse oximetry, CO-metry of exhaled air. To diagnose “hidden” disorders of blood oxygenation, including “hidden” violations of the spectral characteristics of the level of hemoglobin oxygen saturation, 19 male smokers (middle age 54,6±2,05 years) with exacerbation of mixed (68 %) or allergic (32 %) bronchial asthma were examined.The results: the accuracy of the clinical assessment of blood oxygenation in smokers increased significantly after the correction of the SpO2 level to the level of carboxyhemoglobin with the help of a computer program developed by us, which made it possible to diagnose a clinically significant lifethreatening exacerbation of this disease in smoking patients with bronchial asthma, since “hidden” respiratory insufficiency was detected in a timely manner.

Transcutaneous two-wave pulse oximetry is the most popular and prevalent method for studying blood oxygenation. However, during its implementation, smokers do not take into account the level of carboxyhemoglobin, which leads to an erroneous overestimation of hemoglobin saturation with oxygen. The computer program developed by us makes it possible, without the use of additional diagnostic equipment, to correct the results of monitoring blood oxygenation for the level of carboxyhemoglobin, correcting the indicated diagnostic inaccuracy in assessing the saturation of hemoglobin by oxygen in smokers.