Zinc oxide and hydrogen sulfide reaction was researched experimentally. Dynamic characteristics (solid phase mass change per time, temperature change per time inside the reactor, gas volume flow rate on inlet) were obtained for pure ZnO powder and granular sorbent Katalco 32-4-Johnson & Matthey by thermogravimetric analyzer. Pre-exponential factor, energy activation and specific mass flow rate of ZnO were numerically calculated for pure ZnO. Pure ZnO, ZnO 2 SC, and granular sorbent conversion rates were compared. Thermogravimetric experiments with pure ZnO and with ZnO 2 SC were simulated in ANSYS Fluent software. Kinetic constants were input parameters for CFD software. Simulation data and experimental results agree well on sorbent conversion diagram.