The influence of therapy reiki of anxiety on the with HIV / AIDS (ODHA).In general this study attempts to prove influence therapy reiki of anxiety ODHA.Using design pre experimental research with the kind of research one-group pre-post test design. Using techniques sampling simple random sampling, large 16 the sample .The kind of data collected is the primary data ( the anxiety ). Instrument data collection Taylor Manifest of Anxiety Scale (T-MAS). Analysis of data research Wilcoxon Sign Range Test, research results: the anxiety pre test , all respondents ( 100 % ) in a category anxious was , the test the post mild anxiety 3 the ( 20 % ) and 12 people ( 80 % ) still in medium category but score anxiety decline , the analysis show negative ranks = 11 people , it rank = 2 people and ties = the 2 people, p value = 0,017. Any impact of therapy reiki anxiety ODHA on 5 % significance