Contrast-enhanced brain MRI is the imaging modality of choice in diagnosis and posttreatment evaluation, but its role is limited in distinguishing recurrent lesions from postoperative changes. 68 Ga-DOTATATE is a somatostatin analog PET tracer that has high affinity to meningioma expressing somatostatin receptor. Methods: In this case series review, we describe 8 patients with brain MRI showing suspected recurrent meningioma who underwent focused 68 Ga-DOTATATE PET/CT for radiation treatment planning. Results:The combined brain MRI and PET/CT improved the conspicuity of the lesions and aided radiation treatment planning. The time from the initial surgery to PET/CT varied widely, ranging from 1 to 12 y. Three patients underwent PET/CT shortly after the initial surgery (1-3 y) and underwent targeted radiation therapy. Subsequent imaging showed no evidence of recurrence. Four patients had a prolonged time between the PET/CT and the initial surgery (7-12 y), which showed an extensive tumor burden. All 4 patients died shortly after the last PET/CT scan. Conclusion: 68 Ga-DOTATATE PET shows a promising complementary role in detection and treatment planning of recurrent meningioma.
99m Tc-tagged red blood cell scintigraphy is the imaging modality of choice in the diagnosis of active gastrointestinal bleeding. Continuous-flow left ventricular assist devices are the state-of-the-art treatment for advanced heart failure, with gastrointestinal bleeding as the most common complication. Recognition of the distinctive imaging feature of continuous-flow left ventricular assist devices on scintigraphic images can aid diagnosis of gastrointestinal bleeding.
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