Cervical cancer is ranked as the second most common cancer amongst women worldwide and in many low-income countries, it is the most common female cancer. ZedScan, enables us to have a first hand estimation of the accuracy of the system and thereby settling and verifying the claims of the manufacturer.: To prove, easy detection of cervical carcinoma by using EIS as an adjunct to colposcopy giving better detection rates in (CIN)cervical intraepithelial neoplasm with increased diagnostic accuracy.: It was a prospective study done on a sample size of 200 patients. The patients were selected from amongst all the patients attending the Department of Obstetrics & Gynaecology, Base Hospital, Delhi Cantt, either with a clinical indication or an abnormal cervical cytology. All such cases were recruited into the study with histopathology as a gold standard.: Age of patients ranged from 30 to 68 years. Majority of women were aged between 31-40 years (n=135; 67.5%). Mean age of patients was 37.48±6.3 years. Almost all (98.5%) the test patients were married. There were 3 (1.5%) widowed/divorced women. Majority of women were educated up to graduation or above (51%) followed by those educated upto 8th standard (n=53; 26.5%) and those educated upto secondary level (22.5%). BMI of women ranged from 20.11 to 32.30 kg/m2. Majority were in overweight category (n=113; 56.5%). A total of 72 (36%) had normal weight and 15 (7.5%) were obese. Socioeconomically, 88 (44%) belonged to upper middle, 74 (37%) lower middle, 35 (17.5%) to lower and 3 (1.5%) to upper socioeconomic class. Histopathologically, a total of 26 cases were positive and 174 were negative. As compared to histopathology, ZedScan had 11 true positive, 5 false positive, 15 false negative and 169 true negative cases. Correspondingly, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy value of ZedScan for any grade of neoplasia was 42.3%, 97.1%, 68.8%, 90.9% and 90% respectively.: The findings of the study conducted thus suggest that ZedScan has a useful role as an adjunct to Colposcopy in the detection of cervical neoplasia, particularly that of high-grade CINs.
Background: Genital tuberculosis is an unusual extrapulmonary manifestation of tuberculosis, often seen in middle-aged men with renal or pulmonary disease. The most common male genital sites of tuberculous infection are the epididymis and prostate. It is also an important cause of female infertility in the world, especially in developing countries. Majority of infertility cases are due to involvement of the fallopian tubes. Hardly any study has been done to establish correlation between male and female genital TB. We have evaluated the same in severe oligospermic/ azoospermic males and established a definite correlation. Objective was to establish a definite correlation between female and male genital tuberculosis in patients with male factor infertility.Methods: 100 severe oligozoospermic/azoospermic males presenting with infertility between April 2011 and January 2016 were enrolled and worked up for genital tuberculosis. Their female partners were worked up for female genital TB and correlation established.Results: Out of 100 patients with severe oligospermia or azoospermia who tested positive for TB quantiferon gold test. 18% female partners tested positive for TB quantiferon gold test.Conclusions: Tubercular work up of both partners is desired in couples with male factor infertility especially in long standing infertility to achieve optimum pregnancy outcome with ART.
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