The magical plant of Indian spice, Murraya koenigii(curry leaf) family Rutaceae grows throughout the Indian subcontinent. It is used in the treatment or prevention of many diseases including kidney stone, dysentery disorders, renal pain, stomach upsets & morning sickness. It is one of the main components of formulation in the traditional ayurvedic system of medicine since many centuaries. A scrutiny of literature reveals some notable pharmacological activities of plant. These include pharmacological activities such as antioxidant, antidiabetic, antitumor and neuroprotective.The leaves, roots and barks of this plant are rich in source of carbazole alkaloids. The carbazole alkaloids includes koenigin, bicyclomahanim-bicine, cyclomahanimbine, murrayastine, coumarine, koenidine has medicinal activities.

Medicinal plants play significant roles in the prevention of human beings from various pathogenic microorganisms and diseases. The immunomodulators are agents used to modulate the immune system and can be obtained from both natural as well as synthetic origin from plants and chemicals. Alteration within the system is often achieved by immunomodulatory agents from a plant source, low molecular weight compounds like alkaloids and other nitrogen-containing compounds, terpenes, phenols, and high molecular weight compounds like lectins, polysaccharides. The Immune system is a part of the body to detect the pathogen by using a specific receptor to produce an immediate response by the activation of immune components cells, cytokines, and chemokines and also release of an inflammatory mediator. This review also discusses various ethnopharmacological information of traditional medicinal plants being used as immunomodulators.

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