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tologous fat grafting not only provides soft tissue augmentation but may also promote tissue regeneration. Adipose tissue is known to contain multipotent adipose-derived stem cells which can undergo differentiation into various cell lineages. 6 Adiposederived stem cells have also been shown to possess angiogenic, antiapoptotic, and anti-inflammatory characteristics which can favor wound healing. The MAFT technique described by Lee et al 7 has demonstrated promising results with good long-term outcomes in correcting depression of the temporal fossa.The combination of fat grafting and NPWT was first described by Kao et al in an experimental study in rats. Fat grafting and NPWT exerted a synergistic action in significantly accelerating the closure of full-thickness wounds, as NPWT creates a favorable microenvironment conducive to cell proliferation and neovascularization. 4 To the best of our knowledge, our report presents the first case of autologous fat grafting used in conjunction with NPWT for the treatment of scalp LSc. CONCLUSIONThe combination of autologous fat grafting and NPWT appears to be an effective treatment modality for scalp LSc.