The purpose of this study was to evaluate the changes in the clinical and hemato-biochemical parameters of cattle calves suffering from bovine respiratory disease (BRD) compared to pen matched healthy control calves. This study was conducted on 20 calves suffered from BRD and 10 apparently healthy calves. Clinical and physical examination of BRD affected calves revealed significant (P<0.05) increase in pulse rate, body temperature, respiratory rate, anorexia, nasal discharge, coughing, dyspnoea and abnormal lung sounds. Hematological analysis showed that the BRD affected-calves revealed significant (P<0.05) decrease in red blood cells (RBCs) count, haemoglobin (Hb) content, packed cell volume (PCV %) and lymphocytes count, with significant (P<0.05) increase in white blood cells (WBCs), neutrophils, monocytes and eosinophils. Biochemical analysis showed significant (P<0.05) increase in total proteins, globulin, with significant (P<0.05) decrease in albumin and albumin/globulin (A/G) ratio in diseased calves compared to healthy control. Moreover, the BRD affected calves showed significant (P<0.05) increase in liver enzymes activity and kidney function test. In conclusion, the results of this study revealed that the respiratory diseases in calves have severe impacts on several hematological and biochemical parameters.

This study aimed to provide a complete picture of selected hematological and serum biochemical parameters in Ewes from late pregnancy to early postpartum period. This study was carried out on 120 clinically healthy Native sheep in Elgabal -Alakhdar province in Libya. Animals were divided into three groups, group1 included 20 non-pregnant ewes, group2-included 50 pregnant ewes and group3 included 50 lactating ewes. Blood samples were collected three weeks before the expected parturition from group 2and during the 1st month post-partum from group3.whole blood samples were collected for hematological picture, while serum samples were collected for biochemical analysis which included, serum calcium, magnesium and phosphorus and serum glucose, AST, ALT, and cortisol. Significant changes between pre-and post-partum period (pregnant-lactating) were observed in values of hemogram and biochemical parameters including RBCs, MCV, WBCS count, and differential leucocytes show significant change in lymphocyte count, glucose, calcium, phosphorus, magnesium, AST, ALT, and cortisol. Non-significant changes were observed in Hb, HCT, Neutrophil, monocyte, eosinophil, platelet and basophil. These results concluded that transition period has an impact on some hematobiochemical parameters and ewes should be supplemented with minerals including calcium, phosphorous and magnesium. Investigations of major and minor elements may be considered as real indicators for health in transition period in ewes and helps to prevent many diseases at this stage.

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