The aim of our study was to describe the B-mode hepatic ultrasonography of does with subclinical pregnancy toxemia and shed the light on the hematological and protein profile alterations. Based on the blood serum levels of glucose, pregnant does were classified into; Group 1: Thirty pregnant does were used as controls (Their glucose levels were more than 40 mg/dL). Group 2: Twenty-five does were diagnosed as subclinical pregnant toxemic (SCPT) since their glucose values were <40 mg/dL. B-mode of the diagnostic ultrasound scanner was used. Special kits were used for the determination of glucose, total protein and albumin. Liver B-mode ultrasonography of does with SCPT indicated by fatty infiltration among hepatic parenchyma. Rounded margins which were indicated by hepatic enlargement. subclinical pregnancy toxemic does showed significant decreases of RBCs, Hb, MCV, MCH and MCHC and significant increases of PCV, leukocytes, neutrophils and lymphocytes than healthy control pregnant does(P ≤ 0.05). A significant decrease of serum total protein, albumin, and A/G ratio were recorded in subclinical pregnant toxemic does when compared to healthy control one.