Combination of Cross-sectional and retrospective study was conducted from Jan 2021 up to Jun 2021 in Jigjiga city Municipal abattoir and inventory of pharmaceutical drug shops, with the objectives of determining the prevalence of bovine cysticercosis and treatment costs of human taeniasis. Systematic random sampling technique was employed for selecting the study animals, while the Sampling methodology was based on Active abattoir survey and Inventory of pharmaceutical drug shops. From the 520 animals examined at abattoir, the overall prevalence of cysticercus bovis was 2.69% (14/520) with 95% CI of (1.43, 4.29). There was no statistically significant difference in sex, age, body condition score and origin of the animal with the occurrence of C. bovis (P>0.05); From 14 infected cattle with cysticercus bovis, 7 (50%) of cysticercus bovis were in the triceps muscle, 5 (35.71%) in tongue, 1 (7.14%) in biceps muscle and 1 (7.14%) in masseter muscle. Descriptive statistics revealed that a total of 23,063 doses of taenicidal drugs concern a 4-year period (2017-2020) were used for the treatment of human taeniasis which worth 56,933 Ethiopian Birr in the town. Albendazole was employed at a rather high dose, followed by Mebendazole, Praziquantel, and Niclosomide, in that order. The most commonly prescribed medicines for the treatment of taeniasis were albendazole and mebendazole. The discovery highlights the importance of cysticercosis and taeniasis in terms of both economics and public health. To reduce the impact of this parasite, special focus should be paid to raising public awareness and conducting thorough routine meat inspections.