The aim of this study is to evaluate the role of endoscopy in management of multiloculated hydrocephalus. PATIENTS AND METHODS: We reviewed 30 consecutive patients during the period from January 2012 to December 2015 with multiloculated hydrocephalus who underwent neuroendoscopic approach for treatment, in Sohag university Hospital. The patients' clinical outcomes, and complications were reported. RESULTS: There were 30patients (12male18 female).endoscopic septum pellucidum fenestration was done in 9 cases and endoscopic ventricular septal fenestration was done in 21 cases; The success rate was achieved in 25 cases (83.3%). The remaining 5 cases (16.7%) needed a redo the procedure due to the presence of residual compartments not opened and not drained by the existing shunts, no immediate or late postoperative complications and there was no mortality. CONCLUSION:Neuroendoscopic management for multiloculated hydrocephalus can restore communication between isolated intraventricular compartments transforming them into single cavity and one intraventricular catheter can be used , reduce the number of surgical procedures, and improving the quality of life of the patient.

Radical excision of orbitocranial FD is potentially curative with no extra morbidity. It can achieve good aesthetic and functional results with no recurrence.

Objective: To report the results of our first series of patients undergoing a purely endoscopic endonasal approach for pituitary surgery in Sohag University Hospitals. Patients and Methods: We reviewed 20 consecutive patients during the period from January 2017 to January 2020 with pituitary adenoma who underwent purely endoscopic transsphenoidal resection of their lesions. The patients' clinical outcomes, degrees of tumor removal, and complications were reported. Results: There were 18 primary and 2 recurrent adenomas (19 nonfunctioning and 1 functioning GH secreting adenoma). The average degree of gross total removal for tumors was 70%, C.S.F leak occurred in 20%, diabetes insipidus in 10% and sellar hemorrhage in 5%. There was no post-operative mortality, vascular injury, sphenoiditis, septal perforation, epistaxis or general complication. Conclusion: A purely endoscopic approach for pituitary adenoma treatment is a safe and effective alternative to the traditional microscopic procedure.

Introduction: Isolated sphenoid sinus lesions cause symptoms such as headache and visual abnormalities. Endoscopic examination and imaging modalities are mandatory to reach a diagnosis. Objectives: To validate the importance of a direct trans-nasal trans-sphenoid endoscopic approach as a minimally invasive surgical strategy in isolated sphenoid sinus and sellar lesions. Patients & Methods. There are 21 patients in our study, collected over 2 years period. we recorded all patients with isolated sphenoid sinus and sellar lesions. These patients were scheduled for a direct trans-nasal trans-sphenoid endoscopic approach for surgical management. Pituitary adenomas affect ten of them, and isolated sphenoid sinus lesions affect eleven. Complete medical history was taken, as well as general examination and local examination including full ENT examination including endoscopic examination, neurological examination, and ophthalmological examination. Routine laboratory investigations, hormonal assay (in patients with pituitary tumors), and radiological evaluation were done. Results: We faced 21 patients 10 of them had pituitary adenomas and 11 of them had isolated sphenoid sinus lesions. 7 patients had non-secretory pituitary adenomas, 3 patients had secretory adenomas, 4 patients had sphenoid sinus mucoceles, 2 patients had spheno-choanal polyps, 2 patients had isolated sphenoid sinus fungal sinusitis, one patient had a granulomatous lesion, one patient had a neoplastic lesion (squamous cell carcinoma), and one patient had unilateral isolated sphenoiditis. Conclusion: Direct trans-nasal trans-sphenoid endoscopic approach is the preferred option for optimal surgical management of patients with isolated sphenoid sinus and sellar lesions.

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