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Background: Sepsis, a syndrome of dysregulated host response to infection leading to life-threatening organ dysfunction, is having a substantial burden in health system. The outcome in sepsis is often time dependent. None of the clinical manifestations nor the age-old markers like ESR, CRP, etc. have proven diagnostic or prognostic of sepsis. This study aims to assess the role of neutrophil: lymphocyte ratio (NLR) in assessing the severity of sepsis within the initial 24 hrs of admission. Methods: Authors did a retrospective observational study in 208 sepsis patients admitted in the MDICU. The NLR was calculated and the study population was grouped into those with an NLR of more than or equal to 5 and those with less than 5. The patients were also grouped based on the number of organs impaired due to sepsis. The association between these groups were then assessed. Results: 46 patients (60.5%) with single organ involvement had NLR <5; 30 patients (39.5%) had NLR >5; 27 patients (42.2%) with two organ involvement had NLR <5 and 37 patients (57.8%) had NLR >5. Among patients with more than two organ involvement, 8 patients (21.6%) had NLR <5 and 29 patients (78.4%) had NLR >5. It was found that there is statistically significant association between increase in number of organs involved and NLR more than 5. The chi square test value was 15.691 with a p value was less than 0.001. Conclusions: In the current study, we have evaluated the role of NLR in sepsis. NLR calculated on the day of admission is a simple parameter that helps to stratify patients into severe risk category. A significant association was found with higher NLR and the number of organs impairment in sepsis.

The viral infection during influenza includes several complications like primary pneumonitis, ARDS, bacterial pneumonia, otitis media along with severe increase in the ongoing chronic conditions. Fulminant myocarditis as a primary manifestation of H1N1 is rare. We are reporting four cases that developed fulminant viral myocarditis caused by the H1N1 strain of influenza. These four cases were reported between October 2018 and November 2018, during the post-flood time in Kerala.How to cite this articleThomas TP, Kumar S, Anand A, Kiran R, Sabu V, Gaffoor A. A Rare Presentation of Fulminant Viral Myocarditis Associated with H1N1: A Series of Four Cases. IJCCM 2019;23(11): 538–541.

Thermoelectric Power studies of Ni-Mg ferrites having chemical formula Ni_1–xMg_xFeO₄ (x = 0.2, 0.4, 0.6 and 0.8) were investigated from room temperature to well beyond Curie temperature by the differential method. The Seebeck coefficient is negative for all the composition. It clearly speaks that all the considered ferrite compositions behave as n-type semiconductors. Plots of Seebeck coefficient (S) versus temperature shows maximum at Curie temperature. The values of the charge carrier concentration have been computed from the observed values of Seebeck coefficient. The electrical properties of the Ni-Mg mixed ferrites have been measured at room temperature by two-probe method. On the basis of these results an explanation for the conduction mechanism in Ni-Mg mixed ferrites is suggested

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