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Fenugreek (Trigonella foenum-graecum) commonly known as Methi is an annual herb belonging to family Fabaceae. It is cultivated worldwide as a semiarid crop, and its seeds are a common ingredient in dishes from the Indian subcontinent. Its seeds are rich sources of protein dietary fiber, B vitamins, iron and several other dietary minerals. It has many potential medicinal applications in the health industry. It contains compounds which are bioactive such as galactomannan, diosgenin, 4-hydroxyisoleucene, 3-hydroxy-4,5-dimethyl-2(5H) furanone (stolone), etc. Stolone is the flavor compound of fenugreek and it is now a day's commonly used in food industry for various purposes. Its shows antidiabetic, hypoglycemic, antiallergic and labor and lactation induction properties. It decreases the cholesterol level reduces the body weight by decreasing plasma triglycerides tri glycerides. Fenugreek is known to have hypocholesterolemic, antioxidant potency, digestive stimulant action, and hepatoprotective effect. It is anticarcinogenic, antioxidant, antibacterial agent, gastric stimulant, and anti-anorexia agent. Recent research revealed that fenugreek is a valuable medicinal plant of multipurpose uses and may be used for preparing various products such as steroidal hormones. This review presents the major medicinal and other beneficial uses of fenugreek discovered through last many years of research in animal and human subjects as well as in other experimental studies. In this review, we will summarize nutritional, nutraceutical, antioxidant and medicinal properties of fenugreek.

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By the help of surface modification of the nanomaterials specific targeting properties towards specific molecules and receptors in various types of cells could be achieved. It has been suggested that the delivered drugs require low amount to achieve the synergy between both the drugs delivered to cancer cells and tissues. Moreover, the toxic effect of the chemotherapeutic drugs on the normal cells of the body is another major drawback of the treatment. Upon further improvement and optimization of these nanoparticle-based strategies, it will ultimately lead to the prediction of patient's response towards a specific molecular therapy and it will be helpful to observe their responses to personalized therapy. Therefore, theranostics appears to be very helpful and realistic area in the diagnosis and targeted drug delivery of this particular disease.

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