Materials and Methods Study designThis study was performed using data from 44 patients followed up with diagnoses of GHD at the Adıyaman University Education and Research Hospital Pediatric Endocrinology Clinic, Turkey, between August 2016 and February 2021 and receiving GH therapy for at least one year. We took approval for the study from the Adıyaman University Non-Interventional Research Ethical Committee (decision no. 2020/7-7 dated 21/07/2021). We recorded the patients' ages, pubertal development stages, height standard deviation scores (SDS), basal IGF-1 SDS, basal IGFBP-3 SDS, and peak GH response values to clonidine and L-Dopa stimulation tests. Inclusion criteria were the following: 1) The patient's height at the time of presentation <-2 Standard