Introduction
Coronavirus disease 2019 (COVID-19) has emerged as severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). Recently, various complications have been reported. The aim of the current study is to report a rare case of transverse myelitis after recovering from COVID-19.
Case report
A 34-year-old lady, presented with inability to walk for one day duration due to the lower limb weakness. After two weeks from the recovery of COVID-19; she developed progressive intermittent leg pain, paresthesia and weakness on both sides. Brain and cervical MRI showed evidence of a short segment inflammatory enhancing lesion at upper cervical region (at C1 level). The patient was treated conservatively.
Discussion
Transverse myelitis has many different causes, it occurs as an autoimmune phenomenon post-infection and vaccination, or it may result from direct infection or acquired demyelinating disease like multiple sclerosis.
Conclusion
Although it is a sporadic finding, SARS-CoV-2 can cause transverse myelitis. The condition responds to medical therapy.
Introduction and importance:
Osseous metaplasia is an extremely rare finding in the breasts, especially in association with benign tumors. This paper aims to present the first case of synchronous breast fibroadenoma with osseous metaplasia and invasive lobular carcinoma (ILC).
Case presentation:
A 45-year-old female presented with right breast lump for a year. She was hypertensive and had been pregnant for 9 times, in which 5 of them were aborted. Upon examination, there was a painful large mass in right breast. Ultrasound (US) showed multiple masses in the right breast, with the largest one measuring 32 × 16 mm and containing macrocalcification. US also revealed two benign masses in the left breast. Mammography showed an ill-defined asymmetrical density toward the nipple in right breast with two large macrocalcifications. Wide local excision was performed for the right breast, and histopathology examination revealed fibroadenoma with osseous metaplasia, and ILC.
Clinical discussion:
Although osseous metaplasia is rare, it has been observed in various parts of the body that contain soft tissues. To date, only a few cases have been reported in the breast with all of them being associated with malignant neoplasms. It is believed that these heterotrophic bony tissues develop when stromal fibroblasts are transformed by metaplasia into osteoblasts.
Conclusion:
Despite its rarity, benign osseous metaplasia can still occur in the breasts, most commonly in middle-aged females with a painful lump being the first presentation.
Highlights
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