Spent high activity radioactive source (SHARS) is one type of sealed radioactive sources that are typically found inside teletherapy and irradiator devices. As described by the International Atomic Energy Agency (IAEA), these sources are classified as Categories 1 and 2, which pose high risks to human health if they are not managed properly. The radioactive waste management facility (RWMF) does not have the capability of handling SHARS; thus, the RWMF of the Philippine Nuclear Research Institute (PNRI) initiated the safe and secure management of these sources with the assistance of the IAEA through the Nuclear Energy Corporation of South Africa (NECSA). The RWMF performed site preparation for the construction of the mobile hot cell (MHC). The management process involves dismantling the equipment, recovering and encapsulating the source, and placing it inside the long-term storage shields (LTSSs), which are performed inside the MHC. In total, 16 sources were successfully retrieved with a total activity of 204 TBq. The dose rate of both LTSS-1 and LTSS-2 at the surface of the shield was 103 μSv/h and 102 μSv/h, respectively – both of which are below the regulatory limit of 2 mSv/h for the safe transportation of radioactive package. The utilization of the MHC in managing SHARS has made it possible the safe and secure retrieval of SHARSs, given the lack of capability of the Philippines in handling this type of wastes.