A primary effusion lymphoma is a rare type of Non-Hodgkin's lymphoma where serous cavities are involved that cause peritoneal, pleural & pericardial effusions without any lymphadenopathy. They affect immunosuppressive patients with human Herpes virus 8 being the suspected aetiological agent. The prognosis is usually poor despite treatment. Here is a case of an immunocompetent patient with left-sided pleural effusion diagnosed as primary effusion lymphoma who presented with dry cough and breathlessness.

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