Self

All drug discovery methods, right from 'trial-and-error' approach to modern rational synthesis of drugs, make use of animals to check for efficacy and toxicity of compounds. This results in millions of animals being sacrificed every year. Following a global debate on "cruelty of animals", various acts were made and enforced in order to protect animal rights. As a work, around to these animal protection acts, drug discovery scientists started finding alternative approaches to animal studies for research. This review attempts to compile some of the more important non-animal models which are being used for testing safety and efficacy of drugs in preclinical stages.

Blockchain serves as an immutable ledger which allows transactions to take place in a decentralized manner. The proposed solution incorporates the use of Blockchain for Supply Chain Management of Relief Materials after a Disaster. The proposed solution also provides many additional features when compared to the current system like being tamper-proof, providing anonymity and accountability to the users. Our solution incorporates a box-in-box approach whilst keeping tabs via tamper-proof barcodes. Barcodes will be frequently scanned at designated locations. Users also have the facility to track the donated items online through a dedicated website. For blockchain infrastructure, we have used Hyperledger Fabric.