BACKGROUNDPalmoplantar psoriasis that accounts for 3% -4% of all psoriasis cases produces significant functional and social disability. Reduction of pain and improvement in the function of limbs are more important therapeutic goals than complete clearance. This prospective, randomised, controlled study was conducted in Coimbatore Medical College, a tertiary care centre in Tamilnadu. We conducted the study on 50 patients from September 2011 to November 2012. Aims and Objectives-The aims and objectives of the study was to compare the efficacy, to observe the reduction in percentage of psoriasis area and severity index score (PASI SCORE) above 50% and to observe the adverse effects in first 6 months and duration of remission in the next 6 months.