Regadenoson-induced ischemic ST↓ is more common in women and it provides a modest independent prognostic value beyond MPI and clinical parameters. ST↓ ≥ 0.5 mm is a better threshold than ≥ 1.0 mm to define ECG evidence for regadenoson-induced myocardial ischemia.

Correspondence 676.e1 Supplemental Figure 2 Selection of studies for the systematic review. Search Terms: transesophageal echocardiogram + complications; bleeding/hematemesis/melena + esophageal varices; transesophageal echocardiogram + bleeding; transesophageal echocardiogram + esophageal varices.

Among patients selected to undergo coronary angiography, regadenoson-induced ST↓ ≥0.5 mm was associated with higher rates of severe CAD and MACE, irrespective of MPI finding.

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