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In the Gandiolais, the groundwater of the quaternary sands, heavily salted over most of the area, is used to irrigate crops and poses real difficulties for the sustainability of the market gardening system. Secondary salinization of the irrigated soil and the reaction of the absorbing complex depend mainly on the intrinsic parameters, particularly the texture of the soil. The purpose of this article is to analyze the spatial distribution of salinity taking into account the particle size characteristics of the absorbent complex.The hydrogeochemical approach based on the relations of concentration makes it possible to appreciate the process of conservation in situ between the irrigation water and the exploited soil. The results obtained confirmed that the coarse texture of medium-to-fine sand type allows rapid leaching of soluble salts over the entire profile. Soils remain globally calcimagnesian although the irrigation water is globally sodium chloride and potassium or sodium sulphated. However, this high permeability of the complex constitutes a risk of ionic overconcentration in the aquifer. Irrigation returns associated with fertilizers accentuate the mineralization of the groundwater of the quaternary sands.

Introduction: The evolution of primary FSGS is often marked by the occurrence of relapse and corticosteroid resistance and the therapeutic options are numerous and have limited effectiveness. The objective of our study was to assess our practice in this lesion. Patients and Methods: We carried out a retrospective study of patients treated for primary FSGS the period January 1, 2010 to September 30, 2018. The clinical pathological, therapeutic and evolutive characteristics were studied. Results: Fifty-eight patients were included in the study. The average age was 30.74 ± 11.35 years and the sex ratio (M/F) was 2.41. Edema was found in 86.2% and hypertension in 37.9%. The average creatinine was 20.17 ± 16.06 mg/l and the average GFR according to MDRD was 82.43 ± 69.06 ml/min/1.73 m 2 . The average albumin level was 15.11 ± 5.78 g/l and the 24-hour proteinuria was 7.8 ± 3.79 g/24 h. Nephrotic syndrome was the main indication for renal biopsy in 84.48% and the classic form of FSGS was found in 90.9%. The average initial corticosteroid dose was 62.68 ± 10.04 mg/d and the average duration of regression was 11.78 ± 7.40 months. Forty-five patients (77.6%) were corticosensitive (27.6% complete remission and 50% partial remission). Corticosteroid resistance was observed in 19% and corticosteroid dependence in 11.1%. The proportion of relapse was 33.3% within an average of 15.4 ± 9.1 months. Cyclosporine was no longer prescribed as a second-line treatment in 8 patients. Infectious complications were more found in 19%. Two patients had progressed to ESRD and we noted 2 death cases. The male gender was correlated with the occurrence of a relapse. However, the impact of certain factors such as hypertension, proteinuria, hematuria and GFR level has not been demonstrated. Conclusion: The evolution of primary FSGS is unpredictable, often

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